Op-brai130206 2952..2965

Op-brai130206 1..14

1 State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875 China 2 State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China 3 Department of Psychology, Harvard University, Cambridge, MA 02138, USA 4 Centre of Mind/Brain Sciences (CIMeC), University of Tr...

Randomised clinical trial: exploratory phase 2 study of ONO‐2952 in diarrhoea‐predominant irritable bowel syndrome

BACKGROUND ONO-2952 is a novel and selective inhibitor of translocator protein 18 kDa that reduces stress-induced defecation and visceral hyperalgesia in rat models. AIM To evaluate the efficacy and safety of ONO-2952 in females with irritable bowel syndrome with diarrhoea in an exploratory proof-of-concept study. METHODS A randomised, double-blind, placebo-controlled study was conducted at...

انسداد صفراوی داخل کبدی

Attentional Differences in a Driving Hazard Perception Task in Adults with Autism Spectrum Disorders

The current study explored attentional processing of social and non-social stimuli in ASD within the context of a driving hazard perception task. Participants watched videos of road scenes and detected hazards while their eye movements were recorded. Although individuals with ASD demonstrated relatively good detection of driving hazards, they were slower to orient to hazards. Greater attentiona...

A novel G1 checkpoint mediated by the p57 CDK inhibitor and p38 SAPK promotes cell survival upon stress

Comment on: Joaquin M, et al. EMBO J 2012; 31:2952-64.